(CS-049) Use of Oxidized Regenerated Cellulose (ORC)/Collagen/Silver-ORC Dressing in Four Patients With Complex Wounds
Friday, April 28, 2023
7:15 PM - 8:30 PM East Coast USA Time
Introduction: Complex and chronic wounds can be difficult to treat. However, a number of advanced wound dressings are available to help optimize the wound for healing. Oxidized regenerated cellulose (ORC)/collagen (C)/Silver (Ag)-ORC dressings* have been reported to help optimize the wound environment.1-3 ORC/C/Ag-ORC dressing use was examined in 4 patients.
Methods: Antibiotics were given as needed. ORC/C/Ag-ORC dressings were applied to the wound bed followed by a non-adherent, hydrofiber, or foam dressing. Two patients received additional wound coverage. Dry gauze was applied over the dressings in one patient and a two-layer compression wrap was applied over the dressings in the other patient. ORC/C/Ag-C dressings were reapplied every 2 days to twice per week along with secondary dressing and wound coverage changes.
Results: Four patients (age range 67-84 years) presented for care. Patient previous medical history included hernia, obesity, diabetes, hypertension, coronary artery disease, and cancer. Wound types included pressure injury, trauma, and graft failure. Two of the wounds had been present 1-2 months prior to presentation for care. Wound area reduction was observed in all 4 patients. Decreased inflammation was also observed with ORC/C/Ag-C dressing use. Wounds in 2 patients were closed within 42 days of presentation. One wound showed 95% closure by day 21. The remaining wound showed continued wound area reduction by 32 days after presentation.
Discussion: Use of ORC/C/Ag-C dressings contributed to wound area reduction in all 4 patients and complete wound closure in 2 patients.